| General Information of Drug Metabolite (DM) (ID: DM003251) |
| DM Name |
M1-Cis
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidationn |
KW-3902
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| KW-3902 |
DR1907
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Phase 3 |
Congestive heart failure |
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| References |
| 1 |
Simultaneous pharmacokinetic model for rolofylline and both M1-trans and M1-cis metabolites. AAPS J. 2013 Apr;15(2):498-504.
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