| General Information of Drug Metabolite (DM) (ID: DM003357) |
| DM Name |
7- AMlNO NlTRAZEPAM
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Aldehyde oxidase (AOX1)
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DME0052
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| Reduction - Reduction |
Nitrazepam
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[1] , [2] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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N-acetyltransferase 2 (NAT2)
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DME0051
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| Conjugation - Acetylation |
Nitrazepam
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Nitrazepam |
DR1166
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Phase 3 |
Insomnia |
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| References |
| 1 |
Production of superoxide during the metabolism of nitrazepam
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| 2 |
Identification of enzymes responsible for nitrazepam metabolism and toxicity in human
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