| General Information of Drug Metabolite (DM) (ID: DM003538) |
| DM Name |
2-quinolinone-SGX523
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Aldehyde oxidase (AOX1)
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DME0052
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| Unclear - Unclear |
SGX-523
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| SGX-523 |
DR1802
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Phase 1 |
Brain cancer |
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| References |
| 1 |
Species-specific metabolism of SGX523 by aldehyde oxidase and the toxicological implications. Drug Metab Dispos. 2010 Aug;38(8):1277-85.
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