General Information of Drug Metabolite (DM) (ID: DM004130)
DM Name
WIN 55212-2 Metabolite M8a
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Epoxide hydrolase 1 (EPHX1) DME0623 Oxidation - Hydrolyzationn WIN 55212-2 [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
WIN 55212-2 DR1718 Investigative Anaesthesia
References
1 In vitro metabolism of R(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a cannabinoid receptor agonist
2 Toxicokinetics of new psychoactive substances: plasma protein binding, metabolic stability, and human phase I metabolism of the synthetic cannabinoid WIN 55,212-2 studied using in vitro tools and LC-HR-MS/MS

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