| General Information of Drug Metabolite (DM) (ID: DM005039) |
| DM Name |
Capmatinib M19
|
| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Aldehyde oxidase (AOX1)
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DME0052
|
| Unclear - Unclear |
Capmatinib
|
[1] |
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Xanthine dehydrogenase/oxidase (XDH)
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DME0070
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| Unclear - Unclear |
Capmatinib
|
[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Capmatinib |
DR5347
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Approved |
Lung cancer |
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| References |
| 1 |
Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
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