General Information of Drug Metabolite (DM) (ID: DM005160)
DM Name
Remdesivir Alanine Metabolite (Ala-Met; GS-704277)
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Carboxylesterase 1 (CES1) DME0054 Unclear - Unclear Remdesivir [1]
Cathepsin A (CTSA) DME0071 Unclear - Unclear Remdesivir [1]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Adenosine 5'-monophosphoramidase (HINT1) DME0215 Unclear - Unclear Remdesivir [1]
Adenosine 5'-monophosphoramidase (HINT1) DME0215 Unclear Remdesivir [1]
Full List of Drug(s) That Produce This DM By Metabolism
Remdesivir DR5430 Approved Coronavirus Disease 2019 (COVID-19)
References
1 Viral target and metabolism-based rationale for combined use of recently authorized small molecule COVID-19 medicines: Molnupiravir, nirmatrelvir, and remdesivir

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