Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM005184)
DM Name	PB:1-CoA

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
3-MG-CoA hydratase (AUH)	DMEN263	Phenylbutyryl-CoA	Unclear - Unclear	Sodium phenylbutyrate	[1]
Enoyl-CoA hydratase (ECHS1)	DMEN259	Phenylbutyryl-CoA	Unclear - Unclear	Sodium phenylbutyrate	[1]
Long-chain enoyl-CoA hydratase (HADHA)	DMEN265	Phenylbutyryl-CoA	Unclear - Unclear	Sodium phenylbutyrate	[1]

DME(s) Metabolizing This DM

DME Name	DME ID	Product	Reaction	Related Drug	REF
Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD)	DMEN267	PHB-CoA	Unclear - Unclear	Sodium phenylbutyrate	[1]
Short-chain 3-hydroxyacyl-CoA dehydrogenase (HADH)	DMEN266	PHB-CoA	Unclear - Unclear	Sodium phenylbutyrate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Sodium phenylbutyrate		DR5509	Approved		Muscular atrophy

References
1	Identification of enzymes involved in oxidation of phenylbutyrate

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