| General Information of Drug Metabolite (DM) (ID: DM005685) |
| DM Name |
A-1331480
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
ABT-384
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| ABT-384 |
DR1847
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Phase 2 |
Viral hepatitis |
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| References |
| 1 |
Effect of ketoconazole on the pharmacokinetics of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study. Drug Metab Dispos. 2013 May;41(5):1035-45.
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