| General Information of Drug Metabolite (DM) (ID: DM005755) |
| DM Name |
LSN3185556
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Sucrase-isomaltase intestinal (SI)
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DME0457
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| Unclear - Unclear |
M-7403
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| M-7403 |
DR2110
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Phase 1/2 |
Prostate cancer |
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| References |
| 1 |
Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J Biol Chem. 2010 Jun 4;285(23):17763-70.
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| 2 |
A phase I and pharmacokinetic study of taladegib, a Smoothened inhibitor, in Japanese patients with advanced solid tumors
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