| General Information of Drug Metabolite (DM) (ID: DM005979) |
| DM Name |
RSD-1385
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - 4-O-demethylation |
RSD-1235
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| RSD-1235 |
DR1682
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Phase 3 |
Atrial fibrillation |
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| References |
| 1 |
Pharmacokinetics of novel atrial-selective antiarrhythmic agent vernakalant hydrochloride injection (RSD1235): influence of CYP2D6 expression and other factors. J Clin Pharmacol. 2009 Jan;49(1):17-29.
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