General Information of Drug Metabolite (DM) (ID: DM006018)
DM Name
5-chloro-N-ethyl-4-hydroxy-N-(4-hydroxyphenyl)-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
PubChem CID
434122851
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Aromatic hydroxylation TV-5600 [1]
Full List of Drug(s) That Produce This DM By Metabolism
TV-5600 DR0918 Phase 3 Lupus erythematosus
References
1 Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator. Drug Metab Dispos. 2005 Jun;33(6):866-72.

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