| General Information of Drug Metabolite (DM) (ID: DM006019) |
| DM Name |
5-chloro-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
|
| PubChem CID |
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - N-dealkylation |
TV-5600
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| TV-5600 |
DR0918
|
Phase 3 |
Lupus erythematosus |
|
|
| References |
| 1 |
Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator. Drug Metab Dispos. 2005 Jun;33(6):866-72.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
