General Information of Drug Metabolite (DM) (ID: DM006032) |
DM Name |
Apli-da
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Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
DME(s) Producing This DM through Metabolism |
DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - C-dealkylation |
Y-100032
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[1] |
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DME(s) Metabolizing This DM |
DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Hydrolyzationn |
Y-100032
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[1] |
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Full List of Drug(s) That Produce This DM By Metabolism |
Y-100032 |
DR1309
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Phase 3 |
Multiple myeloma |
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References |
1 |
In vitro characterization of the human biotransformation pathways of aplidine, a novel marine anti-cancer drug. Invest New Drugs. 2007 Feb;25(1):9-19.
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