| General Information of Drug Metabolite (DM) (ID: DM006535) |
| DM Name |
Hydroxybenzo[a]pyrene Glucuronidated metabolites
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A10 (UGT1A10)
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DME0075
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| Conjugation - Glucuronidation |
Hydroxybenzo[a]pyrene
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Hydroxybenzo[a]pyrene |
DR1964
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Investigative |
Discovery agent |
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| References |
| 1 |
Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. Drug Metab Dispos. 2006 Jun;34(6):943-9.
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