General Information of Drug Metabolite (DM) (ID: DM006737)
DM Name
6-OH-MXAA glucuronide
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronyltransferase (UGT) DMEN064 Unclear - Unclear ASA-404 [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
ASA-404 DR1664 Phase 2 Prostate cancer
References
1 Predicting pharmacokinetics and drug interactions in patients from in vitro and in vivo models: the experience with 5,6-dimethylxanthenone-4-acetic acid (DMXAA), an anti-cancer drug eliminated mainly by conjugation. Drug Metab Rev. 2002 Nov;34(4):751-90.
2 Preclinical factors affecting the interindividual variability in the clearance of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. Biochem Pharmacol. 2003 Jun 1;65(11):1853-65.

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