| General Information of Drug Metabolite (DM) (ID: DM017001) |
| DM Name |
GS-331007-MP
|
| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Adenosine 5'-monophosphoramidase (HINT1)
|
DME0215
|
| Unclear - Unclear |
Sofosbuvir
|
[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
|
Nucleoside diphosphate kinase (NME4)
|
DMEN006
|
| Unclear - Unclear |
Sofosbuvir
|
[1] |
|
Uridine/cytidine monophosphate kinase (UMPK)
|
DME0456
|
| Unclear - Unclear |
Sofosbuvir
|
[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Sofosbuvir |
DR1495
|
Approved |
Viral hepatitis |
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| References |
| 1 |
Species differences in liver accumulation and metabolism of nucleotide prodrug sofosbuvir
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