| General Information of Drug Metabolite (DM) (ID: DM018105) |
| DM Name |
6-thioinosine triphosphate pyrophosphate
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Thiopurine methyltransferase (TPMT)
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DME0014
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| Unclear - Unclear |
Mercaptopurine
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Mercaptopurine |
DR1031
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Approved |
Acute lymphoblastic leukemia |
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| References |
| 1 |
Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
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| 2 |
6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity
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