| General Information of Drug Metabolite (DM) (ID: DM018151) |
| DM Name |
R-sulfoxide diastereomers
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
RPR-106541
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| RPR-106541 |
DR3022
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Discontinued in Phase 2 |
Asthma |
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| References |
| 1 |
Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis
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