General Information of Drug Metabolite (DM) (ID: DM018152)
DM Name
S-sulfoxide diastereomers
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear RPR-106541 [1]
Full List of Drug(s) That Produce This DM By Metabolism
RPR-106541 DR3022 Discontinued in Phase 2 Asthma
References
1 Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis

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