| General Information of Drug Metabolite (DM) (ID: DM018153) |
| DM Name |
Atipamezole Metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A4 (UGT1A4)
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DME0048
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| Conjugation - N-glucuronidation |
Atipamezole
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[1] |
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UDP-glucuronosyltransferase 2B10 (UGT2B10)
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DME0205
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| Conjugation - N-glucuronidation |
Atipamezole
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Atipamezole |
DR2948
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Discontinued in Phase 2 |
Male sexual disorder |
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| References |
| 1 |
Assessment and Confirmation of Species Difference in Nonlinear Pharmacokinetics of Atipamezole with Physiologically Based Pharmacokinetic Modeling
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