| General Information of Drug Metabolite (DM) (ID: DM018430) |
| DM Name |
Oprozomib Metabolite M8
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
Oprozomib
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Oprozomib |
DR3217
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Phase 2 |
Hodgkin lymphoma |
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| References |
| 1 |
In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s
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