| General Information of Drug Metabolite (DM) (ID: DM018522) |
| DM Name |
Guanfacine Metabolite M6
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidation |
Guanfacine
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Guanfacine |
DR3545
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Phase 4 |
Hepatocellular carcinoma |
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| References |
| 1 |
Metabolite profiling of guanfacine in plasma and urine of healthy Japanese subjects after oral administration of guanfacine extended-release tablets
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