Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM018584)
DM Name	Levallorphan Metabolite M8

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2D6 (CYP2D6)	DME0009	Levallorphan	Unclear - Unclear	Levallorphan	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	Levallorphan	Unclear - Unclear	Levallorphan	[1]

DME(s) Metabolizing This DM

DME Name	DME ID	Product	Reaction	Related Drug	REF
Cytochrome P450 2D6 (CYP2D6)	DME0009	Levallorphan Metabolite M9	Unclear - Unclear	Levallorphan	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	Levallorphan Metabolite M9	Unclear - Unclear	Levallorphan	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Levallorphan		DR5794	Approved		Narcotic depression

References
1	Exploration of catalytic properties of CYP2D6 and CYP3A4 through metabolic studies of levorphanol and levallorphan

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