Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM019047)
DM Name
JTK-853 Metabolite M2
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001
JTK-853
Unclear - Unclear JTK-853 [1]
Full List of Drug(s) That Produce This DM By Metabolism
JTK-853 DR2896 Discontinued in Phase 1 Hepatitis C virus infection
References
1 Pharmacokinetics, Food Effect, Ketoconazole Interaction, and Safety of JTK-853, a Novel Nonnucleoside HCV Polymerase Inhibitor, After Ascending Single and Multiple Doses in Healthy Subjects

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