General Information of Drug Metabolite (DM) (ID: DM019139)
DM Name
Tivantinib Metabolite M8 precursor
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Alcohol dehydrogenase class-II (ADH4) DME0130 Unclear - Unclear Tivantinib [1]
Full List of Drug(s) That Produce This DM By Metabolism
Tivantinib DR3448 Phase 3 Solid tumour/cancer
References
1 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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