| General Information of Drug Metabolite (DM) (ID: DM019286) |
| DM Name |
NITD609 Metabolite M48
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
NITD609
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| NITD609 |
DR3235
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Phase 2 |
Malaria |
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| References |
| 1 |
KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects
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