General Information of Drug Metabolite (DM) (ID: DM019339)
DM Name
KRP-297 Metabolite M1
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear KRP-297 [1]
Dimethylaniline oxidase 3 (FMO3) DME0039 Unclear - Unclear KRP-297 [1]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear KRP-297 [1]
Esterases (ES) DMEN229 Unclear - Unclear KRP-297 [1]
Full List of Drug(s) That Produce This DM By Metabolism
KRP-297 DR2971 Discontinued in Phase 2 Hypertriglyceridaemia
References
1 Absorption, metabolism, and excretion of [14C]MK-0767 (2-methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in humans

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.