| General Information of Drug Metabolite (DM) (ID: DM019602) |
| DM Name |
EPZ-5676 M5
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 (CYP)
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DMEN060
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| Oxidation - Hydroxylation |
EPZ-5676
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| EPZ-5676 |
DR3169
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Phase 1/2 |
Acute myeloid leukaemia |
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| References |
| 1 |
Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor
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