| General Information of Drug Metabolite (DM) (ID: DM001304) |
| DM Name |
P3 semaglutide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Dipeptidyl peptidase IV (DPP4)
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DME0133
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| Oxidation - Hydrolysis; Oxidation |
Semaglutide
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[1] |
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Neprilysin (MME)
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DME0168
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| Oxidation - Hydrolysis; Oxidation |
Semaglutide
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Semaglutide |
DR1473
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Approved |
Diabetes mellitus |
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| References |
| 1 |
Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species. Eur J Pharm Sci. 2017 Jun 15;104:31-41.
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