| General Information of Drug Metabolite (DM) (ID: DM001429) |
| DM Name |
Bisoprolol metabolite M4
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - O-Dealkylation |
Bisoprolol
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - O-Dealkylation |
Bisoprolol
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Bisoprolol |
DR0216
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Approved |
Essential hypertension |
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| References |
| 1 |
Stereoselective metabolism of bisoprolol enantiomers in dogs and humans. Life Sci. 1998;63(13):1097-108.
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