General Information of Drug Metabolite (DM) (ID: DM002850)
DM Name
M-2
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - N-Oxidation Pinacidil [1]
Full List of Drug(s) That Produce This DM By Metabolism
Pinacidil DR1292 Approved Essential hypertension
References
1 Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil. Biochemistry. 2002 Feb 26;41(8):2712-8.

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