General Information of Drug Metabolite (DM) (ID: DM003251)
DM Name
M1-Cis
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Oxidationn KW-3902 [1]
Full List of Drug(s) That Produce This DM By Metabolism
KW-3902 DR1907 Phase 3 Congestive heart failure
References
1 Simultaneous pharmacokinetic model for rolofylline and both M1-trans and M1-cis metabolites. AAPS J. 2013 Apr;15(2):498-504.

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