General Information of Drug Metabolite (DM) (ID: DM003437)
DM Name
A-ketoglutarate
Structure
3D MOL 2D MOL
PubChem CID
155886536
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
isocitrate dehydrogenase (IDH1) DMEN106 Unclear - Unclear DB-053072 [1]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Alpha-ketoglutarate dehydrogenase (OGDH) DMEN107 Unclear - Unclear DB-053072 [1]
Full List of Drug(s) That Produce This DM By Metabolism
DB-053072 DR2449 Phase 1 Prostate cancer
References
1 Metabolic analysis of 13C-labeled pyruvate for noninvasive assessment of mitochondrial function

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