| General Information of Drug Metabolite (DM) (ID: DM004104) |
| DM Name |
KH2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Vitamin K1 2,3-epoxide reductase 1 (VKOR)
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DME0149
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| Reduction - Reduction |
Vitamin K
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Vitamin K-dependent gamma-carboxylase (GGCX)
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DMEN212
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| Oxidation - Oxidationn |
Vitamin K
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Vitamin K |
DR1702
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Investigative |
Discovery agent |
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| References |
| 1 |
Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase
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