| General Information of Drug Metabolite (DM) (ID: DM004993) |
| DM Name |
Asciminib metabolite M37
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidationn ring opening |
ABL001
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| ABL001 |
DR3459
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Phase 3 |
Chronic myelogenous leukaemia |
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| References |
| 1 |
Disposition of asciminib, a potent BCR-ABL1 tyrosine kinase inhibitor, in healthy male subjects
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