| General Information of Drug Metabolite (DM) (ID: DM006611) |
| DM Name |
Clomiphenet of N-demethylation
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Demethylation |
Enclomiphene
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Enclomiphene |
DR0577
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Phase 4 |
Female infertility |
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| References |
| 1 |
CYP2D6 is primarily responsible for the metabolism of clomiphene. Drug Metab Pharmacokinet. 2008;23(2):101-5.
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