| General Information of Drug Metabolite (DM) (ID: DM006737) |
| DM Name |
6-OH-MXAA glucuronide
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronyltransferase (UGT)
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DMEN064
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| Unclear - Unclear |
ASA-404
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| ASA-404 |
DR1664
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Phase 2 |
Prostate cancer |
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| References |
| 1 |
Predicting pharmacokinetics and drug interactions in patients from in vitro and in vivo models: the experience with 5,6-dimethylxanthenone-4-acetic acid (DMXAA), an anti-cancer drug eliminated mainly by conjugation. Drug Metab Rev. 2002 Nov;34(4):751-90.
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| 2 |
Preclinical factors affecting the interindividual variability in the clearance of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. Biochem Pharmacol. 2003 Jun 1;65(11):1853-65.
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