| General Information of Drug Metabolite (DM) (ID: DM017238) |
| DM Name |
ABT-126 metabolite M11
|
| Structure |
|
|
3D MOL is unavailable
|
2D MOL is unavailable
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
UDP-glucuronosyltransferase 1A4 (UGT1A4)
|
DME0048
|
| Conjugation - Glucuronidation |
ABT-126
|
[1] |
|
UDP-glucuronosyltransferase 2B10 (UGT2B10)
|
DME0205
|
| Conjugation - Glucuronidation |
ABT-126
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| ABT-126 |
DR3263
|
Phase 2 |
Alzheimer disease |
|
|
| References |
| 1 |
Metabolism and Disposition of a Novel Selective 7 Neuronal Acetylcholine Receptor Agonist ABT-126 in Humans: Characterization of the Major Roles for Flavin-Containing Monooxygenases and UDP-Glucuronosyl Transferase 1A4 and 2B10 in Catalysis
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
