General Information of Drug Metabolite (DM) (ID: DM017503)
DM Name
Tandospirone metabolite M2
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2D6 (CYP2D6) DME0009 Oxidation - Hydroxylation Tandospirone [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Hydroxylation Tandospirone [1]
Full List of Drug(s) That Produce This DM By Metabolism
Tandospirone DR5755 Approved Anxiety disorder
References
1 Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes

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