General Information of Drug Metabolite (DM) (ID: DM018430)
DM Name
Oprozomib Metabolite M8
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear Oprozomib [1]
Full List of Drug(s) That Produce This DM By Metabolism
Oprozomib DR3217 Phase 2 Hodgkin lymphoma
References
1 In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s

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