General Information of Drug Metabolite (DM) (ID: DM018477)
DM Name
ACU-5149
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2D6 (CYP2D6) DME0009 Oxidation - Hydroxylation Emixustat [1] , [2]
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Hydroxylation Emixustat [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Emixustat DR3375 Phase 2/3 Age-related macular degeneration
References
1 Oxidative Deamination of Emixustat by Human Vascular Adhesion Protein-1/Semicarbazide-Sensitive Amine Oxidase
2 Disposition, profiling and identification of emixustat and its metabolites in humans

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.