| General Information of Drug Metabolite (DM) (ID: DM018976) |
| DM Name |
LEE011 Metabolite M15
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
LEE011
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| LEE011 |
DR3423
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Phase 3 |
Solid tumour/cancer |
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| References |
| 1 |
An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
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