| General Information of Drug Metabolite (DM) (ID: DM019238) |
| DM Name |
INX-09122
|
| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Adenosine 5'-monophosphoramidase (HINT1)
|
DME0215
|
| Unclear - Unclear |
INX-189
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
|
adenosine deaminase-like protein 1 (ADAL1)
|
DMEN818
|
| Unclear - Unclear |
INX-189
|
[1] |
|
adenosine monophosphate deaminase (AMPD)
|
DMEN817
|
| Unclear - Unclear |
INX-189
|
[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| INX-189 |
DR3215
|
Phase 2 |
Hepatitis C virus infection |
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| References |
| 1 |
In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity
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