| General Information of Drug Metabolite (DM) (ID: DM019325) |
| DM Name |
Sinomenine-N-oxide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
SINOMENINE
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| SINOMENINE |
DR3039
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Discontinued in Phase 2 |
Rheumatoid arthritis |
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| References |
| 1 |
Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide
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