| General Information of Drug Metabolite (DM) (ID: DM019615) |
| DM Name |
MAK683 M56
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
MAK683
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| MAK683 |
DR3174
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Phase 1/2 |
Diffuse large B-cell lymphoma |
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| References |
| 1 |
Preclinical pharmacokinetics and metabolism of MAK683, a clinical stage selective oral embryonic ectoderm development (EED) inhibitor for cancer treatment
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