Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR0882)
Drug Name
Ferrum metallicum
Synonyms
Ferrum; Ferrovac E; Ancor B; Armco iron; Atomel 28; Atomel 300M200; Atomel 500M; Atomel 95; Atomiron 44MR; Atomiron 5M; Atomiron AFP 25; Atomiron AFP 5; Copy Powder CS 105-175; Diseases, iron overload; EFV 250; FT 3 (element); HQ (metal); HF 2 (element); Hoeganaes ATW 230; Hoeganaes EH; Iron (Fe); Iron powder; Iron, elemental; PZh-1M3; PZh1M1; PZh2M1; PZh2M2; SUY-B 2; ferrous iron; iron metal; 3ZhP; 7439-89-6; DSP 128B; DSP 135C; F 60 (metal); Fe; GS 6; HL (iron); HS (iron); Iron; LOHA; PZh-2; PZh2M; PZh3; PZh3M; PZh4M; PZhO; Remko
Indication Vitamin deficiency [ICD11: 5B55] Phase 4 [1]
Structure
3D MOL is unavailable 2D MOL
Pharmaceutical Properties Molecular Weight 55.84 Topological Polar Surface Area 0
Heavy Atom Count 1 Rotatable Bond Count 0
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 0
Cross-matching ID
PubChem CID
23925
PubChem SID
3325 ; 819438 ; 820025 ; 821084 ; 821168 ; 821537 ; 823515 ; 823520 ; 824061 ; 824068 ; 824479 ; 824743 ; 825486 ; 826250 ; 826441 ; 827481 ; 827792 ; 829797 ; 829801 ; 829982 ; 831741 ; 832153 ; 832644 ; 834416 ; 835008 ; 835113 ; 835453 ; 835455 ; 837736 ; 838309 ; 838843 ; 839154 ; 839155 ; 839156 ; 839157 ; 839159 ; 841285 ; 5953609 ; 6128693 ; 6435816 ; 6435818 ; 6435820 ; 6436068 ; 6436069 ; 6436071 ; 7433524 ; 8005336 ; 8005353 ; 8005513 ; 8005595
ChEBI ID
ChEBI:18248
CAS Number
7439-89-6
TTD Drug ID
D0Y3TM
Formula
Fe
Canonical SMILES
[Fe]
InChI
1S/Fe
InChIKey
XEEYBQQBJWHFJM-UHFFFAOYSA-N
The Metabolic Roadmap of This Drug
The Full List of Drug Metabolites (DM) of This Drug
DM Name DM ID PubChem ID Reaction DM Level REF
Unclear DM009999 N. A. Unclear 1 [2]
The Full List of Metabolic Reaction (MR) of This Drug
MR ID Reactant Product MR Type DME REF
MR007189 Ferrum metallicum Unclear Unclear FXN [2]
Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug
DME Name DME Info Species Uniprot ID EC Number REF
Friedreich ataxia protein (FXN) DME0416 Homo sapiens
FRDA_HUMAN
1.16.3.1
[2]
References
1 ClinicalTrials.gov (NCT03542825) Oral Lactoferrin Versus Iron Supplementation During Pregnancy.
2 Iron dysregulation in Friedreich ataxia. Semin Pediatr Neurol. 2006 Sep;13(3):166-75.

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