Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR5475)
Drug Name
Penciclovir
Synonyms penciclovir; 39809-25-1; Denavir; Penciclovirum; Vectavir; Penciclovirum [INN-Latin]; Pencyclovir; BRL-39123; BRL 39123; Penciclovir [USAN:INN:BAN]; Penciceovir; UNII-359HUE8FJC; CCRIS 9213; PE2
Indication Human immunodeficiency virus infection [ICD11: 1C60-1C62] Approved [1]
Structure
3D MOL 2D MOL
Pharmaceutical Properties Molecular Weight 253.26 Topological Polar Surface Area 126
Heavy Atom Count 18 Rotatable Bond Count 5
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 5
Cross-matching ID
PubChem CID
135398748
ChEBI ID
CHEBI:7956
CAS Number
39809-25-1
TTD Drug ID
D07BYK
Formula
C10H15N5O3
Canonical SMILES
C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
InChI
InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)
InChIKey
JNTOCHDNEULJHD-UHFFFAOYSA-N
The Metabolic Roadmap of This Drug
The Full List of Drug Metabolites (DM) of This Drug
DM Name DM ID PubChem ID Reaction DM Level REF
Penciclovir-triphosphate DM000140
135434855
Unclear - Unclear 1 [2]
The Full List of Metabolic Reaction (MR) of This Drug
MR ID Reactant Product MR Type DME REF
MR011020 Penciclovir Penciclovir-triphosphate Unclear - Unclear Unclear [2]
References
1 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2 Famciclovir: review of clinical efficacy and safety

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.