Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME) | INTEDE

General Information of Drug (ID: DR5973)
Drug Name	Anifrolumab
Synonyms	.
Indication	Lupus erythematosus [ICD11: 4A40]				Phase 3	[1]

The Metabolic Roadmap of This Drug

The Full List of Drug Metabolites (DM) of This Drug

DM Name	DM ID	PubChem ID	Reaction	DM Level	REF
Amino acids	DM004985	N. A.	Unclear	1	[2]
Smaller oligopeptides	DM004984	N. A.	Unclear	1	[2]

The Full List of Metabolic Reaction (MR) of This Drug

MR ID	Reactant	Product	MR Type	DME	REF
MR005411	Anifrolumab	Smaller oligopeptides	Unclear	Unclear	[2]
MR005412	Anifrolumab	Amino acids	Unclear	Unclear	[2]

References
1	ClinicalTrials.gov (NCT02794285) Long Term Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus (TULIP SLE LTE). U.S. National Institutes of Health.
2	Pharmacokinetics of Monoclonal Antibodies

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