Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)
General Information of Drug (ID: DR0772) | ||||||
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Drug Name |
Gilteritinib
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Synonyms |
Gilteritinib; Gilteritinib (ASP2215); Gilteritinib [USAN:INN]; Xospata; 1254053-43-4; 2-Pyrazinecarboxamide, 6-ethyl-3-((3-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)-; 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; 66D92MGC8M; ASP 2215; ASP-2215; ASP2215; UNII-66D92MGC8M
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Indication | Acute myeloid leukaemia [ICD11: 2A60] | Approved | [1] | |||
Structure | ||||||
3D MOL | 2D MOL | |||||
Pharmaceutical Properties | Molecular Weight | 552.7 | Topological Polar Surface Area | 121 | ||
Heavy Atom Count | 40 | Rotatable Bond Count | 9 | |||
Hydrogen Bond Donor Count | 3 | Hydrogen Bond Acceptor Count | 10 | |||
Cross-matching ID |
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The Metabolic Roadmap of This Drug | |||||
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The Full List of Drug Metabolites (DM) of This Drug | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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The Full List of Metabolic Reaction (MR) of This Drug | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug | ||||||||||||||||||||||||||||||||||
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