Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR1912)
Drug Name
FT-0755769
Synonyms
Chlorid; Chloride (Cl-); Chloride (ion); Chloride anion; Chloride ion (1-); Chloride ions; Chloride(1-); Chlorides; Chlorine anion; Chlorine ion; Chlorine ion(1-); Chlorine(1-); Chlorine, ion; Chlorine, ion (Cl1-); Hydrochloric acid, ion(1-); Perchloride; Q32ZN48698; VEXZGXHMUGYJMC-UHFFFAOYSA-M; chloride; chloride ion; 16887-00-6; AC1L18YJ; AKOS015903642; BDBM26979; C00698; CHEBI:17996; CHEMBL19429; CTK0H5734; Cl(-); Cl-; DTXSID6043969; FT-0755769; I14-18401; MFCD00143949; UNII-Q32ZN48698; c0884
Indication Stomach cancer [ICD11: 2B72] Phase 3 [1]
Structure
3D MOL is unavailable 2D MOL
Pharmaceutical Properties Molecular Weight 35.45 Topological Polar Surface Area 0
Heavy Atom Count 1 Rotatable Bond Count 0
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 1
Cross-matching ID
PubChem CID
312
ChEBI ID
CHEBI:17996
CAS Number
16887-00-6
TTD Drug ID
D07QKK
Formula
Cl-
Canonical SMILES
[Cl-]
InChI
1S/ClH/h1H/p-1
InChIKey
VEXZGXHMUGYJMC-UHFFFAOYSA-M
Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug
DME Name DME Info Species Uniprot ID EC Number REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Homo sapiens
CP3A4_HUMAN
1.14.14.55
[2]
References
1 Isavuconazonium: first global approval. Drugs. 2015 May;75(7):817-22.
2 Metabolism of benzalkonium chlorides by human hepatic cytochromes P450. Chem Res Toxicol. 2019 Dec 16;32(12):2466-2478.

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